Quantifying the dynamics of intrahost HIV-1 sequence evolution is one means of uncovering information about the interaction between HIV-1 and the host immune system.In the chronic phase of infection, common dynamics of sequence divergence and diversity have been reported.We developed an HIV-1 sequence evolution model that simulated the effects of m
Two polychaete species, Hypania invalida and Laonome calida, were found in the Upper Odra River in 2016.Both species were recorded close to a natural river bank down to 1 m depths.They inhabited sandy-gravelly and sandy-muddy sediments.H.invalida is an alien invasive Ponto-Caspian species, Stepping Stones previously known in Poland from the Odra Ri
Compound promiscuity is rationalized as the specific interaction of a small molecule with multiple biological targets Sleeves (as opposed to non-specific binding events) and represents the molecular basis of polypharmacology, an emerging theme in drug discovery and chemical biology.This concise review focuses on Ceiling Light recent studies that ha